diff --git a/cmd/traefik/traefik.go b/cmd/traefik/traefik.go
index 42b48b2d8..a8216d48b 100644
--- a/cmd/traefik/traefik.go
+++ b/cmd/traefik/traefik.go
@@ -19,6 +19,7 @@ import (
 	"github.com/go-acme/lego/v4/challenge"
 	gokitmetrics "github.com/go-kit/kit/metrics"
 	"github.com/sirupsen/logrus"
+	"github.com/spiffe/go-spiffe/v2/workloadapi"
 	"github.com/traefik/paerser/cli"
 	"github.com/traefik/traefik/v2/cmd"
 	"github.com/traefik/traefik/v2/cmd/healthcheck"
@@ -257,7 +258,28 @@ func setupServer(staticConfiguration *static.Configuration) (*server.Server, err
 
 	// Service manager factory
 
-	roundTripperManager := service.NewRoundTripperManager()
+	var spiffeX509Source *workloadapi.X509Source
+	if staticConfiguration.Spiffe != nil && staticConfiguration.Spiffe.WorkloadAPIAddr != "" {
+		log.WithoutContext().
+			WithField("workloadAPIAddr", staticConfiguration.Spiffe.WorkloadAPIAddr).
+			Info("Waiting on SPIFFE SVID delivery")
+
+		spiffeX509Source, err = workloadapi.NewX509Source(
+			ctx,
+			workloadapi.WithClientOptions(
+				workloadapi.WithAddr(
+					staticConfiguration.Spiffe.WorkloadAPIAddr,
+				),
+			),
+		)
+		if err != nil {
+			return nil, fmt.Errorf("unable to create SPIFFE x509 source: %w", err)
+		}
+
+		log.WithoutContext().Info("Successfully obtained SPIFFE SVID.")
+	}
+
+	roundTripperManager := service.NewRoundTripperManager(spiffeX509Source)
 	acmeHTTPHandler := getHTTPChallengeHandler(acmeProviders, httpChallengeProvider)
 	managerFactory := service.NewManagerFactory(*staticConfiguration, routinesPool, metricsRegistry, roundTripperManager, acmeHTTPHandler)
 
diff --git a/docs/content/https/spiffe.md b/docs/content/https/spiffe.md
new file mode 100644
index 000000000..9d70e5a20
--- /dev/null
+++ b/docs/content/https/spiffe.md
@@ -0,0 +1,54 @@
+---
+title: "Traefik SPIFFE Documentation"
+description: "Learn how to configure Traefik to use SPIFFE. Read the technical documentation."
+---
+
+# SPIFFE
+
+Secure the backend connection with SPIFFE.
+{: .subtitle }
+
+[SPIFFE](https://spiffe.io/docs/latest/spiffe-about/overview/) (Secure Production Identity Framework For Everyone), 
+provides a secure identity in the form of a specially crafted X.509 certificate, 
+to every workload in an environment.
+
+Traefik is able to connect to the Workload API to obtain an x509-SVID used to secure the connection with SPIFFE enabled backends.
+
+## Configuration
+
+### General
+
+Enabling SPIFFE is part of the [static configuration](../getting-started/configuration-overview.md#the-static-configuration).
+It can be defined by using a file (YAML or TOML) or CLI arguments.
+
+### Workload API
+
+The `workloadAPIAddr` configuration defines the address of the SPIFFE [Workload API](https://spiffe.io/docs/latest/spiffe-about/spiffe-concepts/#spiffe-workload-api).
+
+!!! info "Enabling SPIFFE in ServersTransports"
+
+    Enabling SPIFFE does not imply that backend connections are going to use it automatically.
+    Each [ServersTransport](../routing/services/index.md#serverstransport_1) that is meant to be secured with SPIFFE must [explicitly](../routing/services/index.md#spiffe) enable it.
+
+!!! warning "SPIFFE can cause Traefik to stall"
+	When using SPIFFE,
+	Traefik will wait for the first SVID to be delivered before starting.
+	If Traefik is hanging when waiting on SPIFFE SVID delivery,
+	please double check that it is correctly registered as workload in your SPIFFE infrastructure.
+
+```yaml tab="File (YAML)"
+## Static configuration
+spiffe:
+    workloadAPIAddr: localhost
+```
+
+```toml tab="File (TOML)"
+## Static configuration
+[spiffe]
+    workloadAPIAddr: localhost
+```
+
+```bash tab="CLI"
+## Static configuration
+--spiffe.workloadAPIAddr=localhost
+```
diff --git a/docs/content/reference/dynamic-configuration/file.toml b/docs/content/reference/dynamic-configuration/file.toml
index 4634afea2..c197e75cb 100644
--- a/docs/content/reference/dynamic-configuration/file.toml
+++ b/docs/content/reference/dynamic-configuration/file.toml
@@ -301,12 +301,18 @@
       [[http.serversTransports.ServersTransport0.certificates]]
         certFile = "foobar"
         keyFile = "foobar"
+
       [http.serversTransports.ServersTransport0.forwardingTimeouts]
         dialTimeout = "42s"
         responseHeaderTimeout = "42s"
         idleConnTimeout = "42s"
         readIdleTimeout = "42s"
         pingTimeout = "42s"
+
+      [http.serversTransports.ServersTransport0.spiffe]
+        ids = ["foobar", "foobar"]
+        trustDomain = "foobar"
+
     [http.serversTransports.ServersTransport1]
       serverName = "foobar"
       insecureSkipVerify = true
@@ -322,6 +328,7 @@
       [[http.serversTransports.ServersTransport1.certificates]]
         certFile = "foobar"
         keyFile = "foobar"
+
       [http.serversTransports.ServersTransport1.forwardingTimeouts]
         dialTimeout = "42s"
         responseHeaderTimeout = "42s"
@@ -329,6 +336,10 @@
         readIdleTimeout = "42s"
         pingTimeout = "42s"
 
+      [http.serversTransports.ServersTransport1.spiffe]
+        ids = ["foobar", "foobar"]
+        trustDomain = "foobar"
+
 [tcp]
   [tcp.routers]
     [tcp.routers.TCPRouter0]
diff --git a/docs/content/reference/dynamic-configuration/file.yaml b/docs/content/reference/dynamic-configuration/file.yaml
index 807bc8a14..fc446ec0f 100644
--- a/docs/content/reference/dynamic-configuration/file.yaml
+++ b/docs/content/reference/dynamic-configuration/file.yaml
@@ -345,6 +345,12 @@ http:
         pingTimeout: 42s
       disableHTTP2: true
       peerCertURI: foobar
+      spiffe:
+        ids:
+          - foobar
+          - foobar
+        trustDomain: foobar
+
     ServersTransport1:
       serverName: foobar
       insecureSkipVerify: true
@@ -365,6 +371,12 @@ http:
         pingTimeout: 42s
       disableHTTP2: true
       peerCertURI: foobar
+      spiffe:
+        ids:
+          - foobar
+          - foobar
+        trustDomain: foobar
+
 tcp:
   routers:
     TCPRouter0:
diff --git a/docs/content/reference/dynamic-configuration/kubernetes-crd-definition-v1.yml b/docs/content/reference/dynamic-configuration/kubernetes-crd-definition-v1.yml
index 17dc336f6..983a678b8 100644
--- a/docs/content/reference/dynamic-configuration/kubernetes-crd-definition-v1.yml
+++ b/docs/content/reference/dynamic-configuration/kubernetes-crd-definition-v1.yml
@@ -1679,6 +1679,19 @@ spec:
                 description: ServerName defines the server name used to contact the
                   server.
                 type: string
+              spiffe:
+                description: Spiffe defines the SPIFFE configuration.
+                properties:
+                  ids:
+                    description: IDs defines the allowed SPIFFE IDs (takes precedence
+                      over the SPIFFE TrustDomain).
+                    items:
+                      type: string
+                    type: array
+                  trustDomain:
+                    description: TrustDomain defines the allowed SPIFFE trust domain.
+                    type: string
+                type: object
             type: object
         required:
         - metadata
diff --git a/docs/content/reference/dynamic-configuration/kv-ref.md b/docs/content/reference/dynamic-configuration/kv-ref.md
index f72e024e4..d83a15476 100644
--- a/docs/content/reference/dynamic-configuration/kv-ref.md
+++ b/docs/content/reference/dynamic-configuration/kv-ref.md
@@ -186,6 +186,9 @@
 | `traefik/http/serversTransports/ServersTransport0/rootCAs/0` | `foobar` |
 | `traefik/http/serversTransports/ServersTransport0/rootCAs/1` | `foobar` |
 | `traefik/http/serversTransports/ServersTransport0/serverName` | `foobar` |
+| `traefik/http/serversTransports/ServersTransport0/spiffe/ids/0` | `foobar` |
+| `traefik/http/serversTransports/ServersTransport0/spiffe/ids/1` | `foobar` |
+| `traefik/http/serversTransports/ServersTransport0/spiffe/trustDomain` | `foobar` |
 | `traefik/http/serversTransports/ServersTransport1/certificates/0/certFile` | `foobar` |
 | `traefik/http/serversTransports/ServersTransport1/certificates/0/keyFile` | `foobar` |
 | `traefik/http/serversTransports/ServersTransport1/certificates/1/certFile` | `foobar` |
@@ -202,6 +205,9 @@
 | `traefik/http/serversTransports/ServersTransport1/rootCAs/0` | `foobar` |
 | `traefik/http/serversTransports/ServersTransport1/rootCAs/1` | `foobar` |
 | `traefik/http/serversTransports/ServersTransport1/serverName` | `foobar` |
+| `traefik/http/serversTransports/ServersTransport1/spiffe/ids/0` | `foobar` |
+| `traefik/http/serversTransports/ServersTransport1/spiffe/ids/1` | `foobar` |
+| `traefik/http/serversTransports/ServersTransport1/spiffe/trustDomain` | `foobar` |
 | `traefik/http/services/Service01/loadBalancer/healthCheck/followRedirects` | `true` |
 | `traefik/http/services/Service01/loadBalancer/healthCheck/headers/name0` | `foobar` |
 | `traefik/http/services/Service01/loadBalancer/healthCheck/headers/name1` | `foobar` |
diff --git a/docs/content/reference/dynamic-configuration/traefik.containo.us_serverstransports.yaml b/docs/content/reference/dynamic-configuration/traefik.containo.us_serverstransports.yaml
index afc038496..f23d345ce 100644
--- a/docs/content/reference/dynamic-configuration/traefik.containo.us_serverstransports.yaml
+++ b/docs/content/reference/dynamic-configuration/traefik.containo.us_serverstransports.yaml
@@ -113,6 +113,19 @@ spec:
                 description: ServerName defines the server name used to contact the
                   server.
                 type: string
+              spiffe:
+                description: Spiffe defines the SPIFFE configuration.
+                properties:
+                  ids:
+                    description: IDs defines the allowed SPIFFE IDs (takes precedence
+                      over the SPIFFE TrustDomain).
+                    items:
+                      type: string
+                    type: array
+                  trustDomain:
+                    description: TrustDomain defines the allowed SPIFFE trust domain.
+                    type: string
+                type: object
             type: object
         required:
         - metadata
diff --git a/docs/content/reference/static-configuration/cli-ref.md b/docs/content/reference/static-configuration/cli-ref.md
index 444a2ce84..eb7831f52 100644
--- a/docs/content/reference/static-configuration/cli-ref.md
+++ b/docs/content/reference/static-configuration/cli-ref.md
@@ -984,6 +984,18 @@ If non-zero, controls the maximum idle (keep-alive) to keep per-host. If zero, D
 `--serverstransport.rootcas`:  
 Add cert file for self-signed certificate.
 
+`--serverstransport.spiffe`:  
+Defines the SPIFFE configuration. (Default: ```false```)
+
+`--serverstransport.spiffe.ids`:  
+Defines the allowed SPIFFE IDs (takes precedence over the SPIFFE TrustDomain).
+
+`--serverstransport.spiffe.trustdomain`:  
+Defines the allowed SPIFFE trust domain.
+
+`--spiffe.workloadapiaddr`:  
+Defines the workload API address.
+
 `--tracing`:  
 OpenTracing configuration. (Default: ```false```)
 
diff --git a/docs/content/reference/static-configuration/env-ref.md b/docs/content/reference/static-configuration/env-ref.md
index 3cae404b1..e23990497 100644
--- a/docs/content/reference/static-configuration/env-ref.md
+++ b/docs/content/reference/static-configuration/env-ref.md
@@ -984,6 +984,18 @@ If non-zero, controls the maximum idle (keep-alive) to keep per-host. If zero, D
 `TRAEFIK_SERVERSTRANSPORT_ROOTCAS`:  
 Add cert file for self-signed certificate.
 
+`TRAEFIK_SERVERSTRANSPORT_SPIFFE`:  
+Defines the SPIFFE configuration. (Default: ```false```)
+
+`TRAEFIK_SERVERSTRANSPORT_SPIFFE_IDS`:  
+Defines the allowed SPIFFE IDs (takes precedence over the SPIFFE TrustDomain).
+
+`TRAEFIK_SERVERSTRANSPORT_SPIFFE_TRUSTDOMAIN`:  
+Defines the allowed SPIFFE trust domain.
+
+`TRAEFIK_SPIFFE_WORKLOADAPIADDR`:  
+Defines the workload API address.
+
 `TRAEFIK_TRACING`:  
 OpenTracing configuration. (Default: ```false```)
 
diff --git a/docs/content/routing/overview.md b/docs/content/routing/overview.md
index b49c9748b..3816c1e70 100644
--- a/docs/content/routing/overview.md
+++ b/docs/content/routing/overview.md
@@ -325,6 +325,61 @@ serversTransport:
 --serversTransport.maxIdleConnsPerHost=7
 ```
 
+### `spiffe`
+
+Please note that [SPIFFE](../https/spiffe.md) must be enabled in the static configuration 
+before using it to secure the connection between Traefik and the backends.  
+
+#### `spiffe.ids`
+
+_Optional_
+
+`ids` defines the allowed SPIFFE IDs.
+This takes precedence over the SPIFFE TrustDomain.
+
+```yaml tab="File (YAML)"
+## Static configuration
+serversTransport:
+    spiffe:
+      ids:
+        - spiffe://trust-domain/id1
+        - spiffe://trust-domain/id2
+```
+
+```toml tab="File (TOML)"
+## Static configuration
+[serversTransport.spiffe]
+  ids = ["spiffe://trust-domain/id1", "spiffe://trust-domain/id2"]
+```
+
+```bash tab="CLI"
+## Static configuration
+--serversTransport.spiffe.ids=spiffe://trust-domain/id1,spiffe://trust-domain/id2
+```
+
+#### `spiffe.trustDomain`
+
+_Optional_
+
+`trustDomain` defines the allowed SPIFFE trust domain.
+
+```yaml tab="File (YAML)"
+## Static configuration
+serversTransport:
+  trustDomain: spiffe://trust-domain
+```
+
+```toml tab="File (TOML)"
+## Static configuration
+[serversTransport.spiffe]
+  trustDomain = "spiffe://trust-domain"
+```
+
+```bash tab="CLI"
+## Static configuration
+--serversTransport.spiffe.trustDomain=spiffe://trust-domain
+```
+
 ### `forwardingTimeouts`
 
 `forwardingTimeouts` is about a number of timeouts relevant to when forwarding requests to the backend servers.
diff --git a/docs/content/routing/services/index.md b/docs/content/routing/services/index.md
index 7186765f1..800471cf8 100644
--- a/docs/content/routing/services/index.md
+++ b/docs/content/routing/services/index.md
@@ -776,6 +776,82 @@ spec:
     peerCertURI: foobar
 ```
 
+#### `spiffe`
+
+Please note that [SPIFFE](../../https/spiffe.md) must be enabled in the static configuration
+before using it to secure the connection between Traefik and the backends.
+
+##### `spiffe.ids`
+
+_Optional_
+
+`ids` defines the allowed SPIFFE IDs. 
+This takes precedence over the SPIFFE TrustDomain.
+
+```yaml tab="File (YAML)"
+## Dynamic configuration
+http:
+  serversTransports:
+    mytransport:
+      spiffe:
+        ids:
+          - spiffe://trust-domain/id1
+          - spiffe://trust-domain/id2
+```
+
+```toml tab="File (TOML)"
+## Dynamic configuration
+[http.serversTransports.mytransport.spiffe]
+  ids = ["spiffe://trust-domain/id1", "spiffe://trust-domain/id2"]
+```
+
+```yaml tab="Kubernetes"
+apiVersion: traefik.containo.us/v1alpha1
+kind: ServersTransport
+metadata:
+  name: mytransport
+  namespace: default
+
+spec:
+    spiffe:
+      ids:
+        - spiffe://trust-domain/id1
+        - spiffe://trust-domain/id2
+```
+
+##### `spiffe.trustDomain`
+
+_Optional_
+
+`trustDomain` defines the allowed SPIFFE trust domain.
+
+```yaml tab="File (YAML)"
+## Dynamic configuration
+http:
+  serversTransports:
+    mytransport:
+        spiffe:
+          trustDomain: spiffe://trust-domain
+```
+
+```toml tab="File (TOML)"
+## Dynamic configuration
+[http.serversTransports.mytransport.spiffe]
+  trustDomain = "spiffe://trust-domain"
+```
+
+```yaml tab="Kubernetes"
+apiVersion: traefik.containo.us/v1alpha1
+kind: ServersTransport
+metadata:
+  name: mytransport
+  namespace: default
+
+spec:
+    spiffe:
+      trustDomain: "spiffe://trust-domain"
+```
+
 #### `forwardingTimeouts`
 
 `forwardingTimeouts` are the timeouts applied when forwarding requests to the servers.
diff --git a/docs/mkdocs.yml b/docs/mkdocs.yml
index 218154bc3..549fa367c 100644
--- a/docs/mkdocs.yml
+++ b/docs/mkdocs.yml
@@ -110,6 +110,7 @@ nav:
       - 'TLS': 'https/tls.md'
       - 'Let''s Encrypt': 'https/acme.md'
       - 'Tailscale': 'https/tailscale.md'
+      - 'SPIFFE': 'https/spiffe.md'
   - 'Middlewares':
     - 'Overview': 'middlewares/overview.md'
     - 'HTTP':
diff --git a/go.mod b/go.mod
index 35ee71c30..6377a2a2c 100644
--- a/go.mod
+++ b/go.mod
@@ -57,6 +57,7 @@ require (
 	github.com/prometheus/client_model v0.2.0
 	github.com/rancher/go-rancher-metadata v0.0.0-20200311180630-7f4c936a06ac
 	github.com/sirupsen/logrus v1.8.1
+	github.com/spiffe/go-spiffe/v2 v2.1.1
 	github.com/stretchr/testify v1.8.0
 	github.com/stvp/go-udp-testing v0.0.0-20191102171040-06b61409b154
 	github.com/tailscale/tscert v0.0.0-20220316030059-54bbcb9f74e2
@@ -76,7 +77,7 @@ require (
 	golang.org/x/text v0.3.7
 	golang.org/x/time v0.0.0-20220224211638-0e9765cccd65
 	golang.org/x/tools v0.1.6-0.20210726203631-07bc1bf47fb2
-	google.golang.org/grpc v1.41.0
+	google.golang.org/grpc v1.46.0
 	gopkg.in/DataDog/dd-trace-go.v1 v1.38.1
 	gopkg.in/fsnotify.v1 v1.4.7
 	gopkg.in/yaml.v3 v3.0.1
@@ -111,7 +112,7 @@ require (
 	github.com/HdrHistogram/hdrhistogram-go v1.1.2 // indirect
 	github.com/Masterminds/goutils v1.1.1 // indirect
 	github.com/Masterminds/semver/v3 v3.1.1 // indirect
-	github.com/Microsoft/go-winio v0.5.1 // indirect
+	github.com/Microsoft/go-winio v0.5.2 // indirect
 	github.com/Microsoft/hcsshim v0.8.23 // indirect
 	github.com/OpenDNS/vegadns2client v0.0.0-20180418235048-a3fa4a771d87 // indirect
 	github.com/Shopify/sarama v1.23.1 // indirect
@@ -311,6 +312,7 @@ require (
 	github.com/xeipuuv/gojsonschema v1.2.0 // indirect
 	github.com/yandex-cloud/go-genproto v0.0.0-20220805142335-27b56ddae16f // indirect
 	github.com/yandex-cloud/go-sdk v0.0.0-20220805164847-cf028e604997 // indirect
+	github.com/zeebo/errs v1.2.2 // indirect
 	go.elastic.co/apm/module/apmhttp v1.13.1 // indirect
 	go.elastic.co/fastjson v1.1.0 // indirect
 	go.etcd.io/etcd/api/v3 v3.5.4 // indirect
diff --git a/go.sum b/go.sum
index e15dae5df..9ae168cae 100644
--- a/go.sum
+++ b/go.sum
@@ -153,8 +153,9 @@ github.com/Microsoft/go-winio v0.4.17-0.20210211115548-6eac466e5fa3/go.mod h1:JP
 github.com/Microsoft/go-winio v0.4.17-0.20210324224401-5516f17a5958/go.mod h1:JPGBdM1cNvN/6ISo+n8V5iA4v8pBzdOpzfwIujj1a84=
 github.com/Microsoft/go-winio v0.4.17/go.mod h1:JPGBdM1cNvN/6ISo+n8V5iA4v8pBzdOpzfwIujj1a84=
 github.com/Microsoft/go-winio v0.5.0/go.mod h1:JPGBdM1cNvN/6ISo+n8V5iA4v8pBzdOpzfwIujj1a84=
-github.com/Microsoft/go-winio v0.5.1 h1:aPJp2QD7OOrhO5tQXqQoGSJc+DjDtWTGLOmNyAm6FgY=
 github.com/Microsoft/go-winio v0.5.1/go.mod h1:JPGBdM1cNvN/6ISo+n8V5iA4v8pBzdOpzfwIujj1a84=
+github.com/Microsoft/go-winio v0.5.2 h1:a9IhgEQBCUEk6QCdml9CiJGhAws+YwffDHEMp1VMrpA=
+github.com/Microsoft/go-winio v0.5.2/go.mod h1:WpS1mjBmmwHBEWmogvA2mj8546UReBk4v8QkMxJ6pZY=
 github.com/Microsoft/hcsshim v0.8.6/go.mod h1:Op3hHsoHPAvb6lceZHDtd9OkTew38wNoXnJs8iY7rUg=
 github.com/Microsoft/hcsshim v0.8.7-0.20190325164909-8abdbb8205e4/go.mod h1:Op3hHsoHPAvb6lceZHDtd9OkTew38wNoXnJs8iY7rUg=
 github.com/Microsoft/hcsshim v0.8.7/go.mod h1:OHd7sQqRFrYd3RmSgbgji+ctCwkbq2wbEYNSzOYtcBQ=
@@ -338,8 +339,12 @@ github.com/cncf/udpa/go v0.0.0-20191209042840-269d4d468f6f/go.mod h1:M8M6+tZqaGX
 github.com/cncf/udpa/go v0.0.0-20200313221541-5f7e5dd04533/go.mod h1:WmhPx2Nbnhtbo57+VJT5O0JRkEi1Wbu0z5j0R8u5Hbk=
 github.com/cncf/udpa/go v0.0.0-20200629203442-efcf912fb354/go.mod h1:WmhPx2Nbnhtbo57+VJT5O0JRkEi1Wbu0z5j0R8u5Hbk=
 github.com/cncf/udpa/go v0.0.0-20201120205902-5459f2c99403/go.mod h1:WmhPx2Nbnhtbo57+VJT5O0JRkEi1Wbu0z5j0R8u5Hbk=
+github.com/cncf/udpa/go v0.0.0-20210930031921-04548b0d99d4/go.mod h1:6pvJx4me5XPnfI9Z40ddWsdw2W/uZgQLFXToKeRcDiI=
 github.com/cncf/xds/go v0.0.0-20210312221358-fbca930ec8ed/go.mod h1:eXthEFrGJvWHgFFCl3hGmgk+/aYT6PnTQLykKQRLhEs=
 github.com/cncf/xds/go v0.0.0-20210805033703-aa0b78936158/go.mod h1:eXthEFrGJvWHgFFCl3hGmgk+/aYT6PnTQLykKQRLhEs=
+github.com/cncf/xds/go v0.0.0-20210922020428-25de7278fc84/go.mod h1:eXthEFrGJvWHgFFCl3hGmgk+/aYT6PnTQLykKQRLhEs=
+github.com/cncf/xds/go v0.0.0-20211001041855-01bcc9b48dfe/go.mod h1:eXthEFrGJvWHgFFCl3hGmgk+/aYT6PnTQLykKQRLhEs=
+github.com/cncf/xds/go v0.0.0-20211011173535-cb28da3451f1/go.mod h1:eXthEFrGJvWHgFFCl3hGmgk+/aYT6PnTQLykKQRLhEs=
 github.com/cockroachdb/apd v1.1.0/go.mod h1:8Sl8LxpKi29FqWXR16WEFZRNSz3SoPzUzeMeY4+DwBQ=
 github.com/cockroachdb/datadriven v0.0.0-20190809214429-80d97fb3cbaa/go.mod h1:zn76sxSg3SzpJ0PPJaLDCu+Bu0Lg3sKTORVIj19EIF8=
 github.com/codahale/hdrhistogram v0.0.0-20160425231609-f8ad88b59a58/go.mod h1:sE/e/2PUdi/liOCUjSTXgM1o87ZssimdTWN964YiIeI=
@@ -629,6 +634,7 @@ github.com/envoyproxy/go-control-plane v0.9.9-0.20201210154907-fd9021fe5dad/go.m
 github.com/envoyproxy/go-control-plane v0.9.9-0.20210217033140-668b12f5399d/go.mod h1:cXg6YxExXjJnVBQHBLXeUAgxn2UodCpnH306RInaBQk=
 github.com/envoyproxy/go-control-plane v0.9.9-0.20210512163311-63b5d3c536b0/go.mod h1:hliV/p42l8fGbc6Y9bQ70uLwIvmJyVE5k4iMKlh8wCQ=
 github.com/envoyproxy/go-control-plane v0.9.10-0.20210907150352-cf90f659a021/go.mod h1:AFq3mo9L8Lqqiid3OhADV3RfLJnjiw63cSpi+fDTRC0=
+github.com/envoyproxy/go-control-plane v0.10.2-0.20220325020618-49ff273808a1/go.mod h1:KJwIaB5Mv44NWtYuAOFCVOjcI94vtpEz2JU/D2v6IjE=
 github.com/envoyproxy/protoc-gen-validate v0.1.0/go.mod h1:iSmxcyjqTsJpI2R4NaDN7+kN2VEUnK/pcBlmesArF7c=
 github.com/erikstmartin/go-testdb v0.0.0-20160219214506-8d10e4a1bae5/go.mod h1:a2zkGnVExMxdzMo3M0Hi/3sEU+cWnZpSni0O6/Yb/P0=
 github.com/evanphx/json-patch v0.5.2/go.mod h1:ZWS5hhDbVDyob71nXKNL0+PWn6ToqBHMikGIFbs31qQ=
@@ -1890,6 +1896,8 @@ github.com/spf13/viper v1.7.0/go.mod h1:8WkrPz2fc9jxqZNCJI/76HCieCp4Q8HaLFoCha5q
 github.com/spf13/viper v1.7.1/go.mod h1:8WkrPz2fc9jxqZNCJI/76HCieCp4Q8HaLFoCha5qpdg=
 github.com/spf13/viper v1.8.1 h1:Kq1fyeebqsBfbjZj4EL7gj2IO0mMaiyjYUWcUsl2O44=
 github.com/spf13/viper v1.8.1/go.mod h1:o0Pch8wJ9BVSWGQMbra6iw0oQ5oktSIBaujf1rJH9Ns=
+github.com/spiffe/go-spiffe/v2 v2.1.1 h1:RT9kM8MZLZIsPTH+HKQEP5yaAk3yd/VBzlINaRjXs8k=
+github.com/spiffe/go-spiffe/v2 v2.1.1/go.mod h1:5qg6rpqlwIub0JAiF1UK9IMD6BpPTmvG6yfSgDBs5lg=
 github.com/stefanberger/go-pkcs11uri v0.0.0-20201008174630-78d3cae3a980/go.mod h1:AO3tvPzVZ/ayst6UlUKUv6rcPQInYe3IknH3jYhAKu8=
 github.com/stoewer/go-strcase v1.2.0/go.mod h1:IBiWB2sKIp3wVVQ3Y035++gc+knqhUQag1KpM8ahLw8=
 github.com/streadway/amqp v0.0.0-20190404075320-75d898a42a94/go.mod h1:AZpEONHx3DKn8O/DFsRAY58/XVQiIPMTMB1SddzLXVw=
@@ -2059,6 +2067,8 @@ github.com/yvasiyarov/newrelic_platform_go v0.0.0-20140908184405-b21fdbd4370f/go
 github.com/zclconf/go-cty v1.2.0/go.mod h1:hOPWgoHbaTUnI5k4D2ld+GRpFJSCe6bCM7m1q/N4PQ8=
 github.com/zclconf/go-cty v1.4.0/go.mod h1:nHzOclRkoj++EU9ZjSrZvRG0BXIWt8c7loYc0qXAFGQ=
 github.com/zclconf/go-cty v1.7.1/go.mod h1:VDR4+I79ubFBGm1uJac1226K5yANQFHeauxPBoP54+o=
+github.com/zeebo/errs v1.2.2 h1:5NFypMTuSdoySVTqlNs1dEoU21QVamMQJxW/Fii5O7g=
+github.com/zeebo/errs v1.2.2/go.mod h1:sgbWHsvVuTPHcqJJGQ1WhI5KbWlHYz+2+2C/LSEtCw4=
 github.com/zenazn/goji v0.9.0/go.mod h1:7S9M489iMyHBNxwZnk9/EHS098H4/F6TATF2mIxtB1Q=
 github.com/zenazn/goji v1.0.1/go.mod h1:7S9M489iMyHBNxwZnk9/EHS098H4/F6TATF2mIxtB1Q=
 github.com/ziutek/mymysql v1.5.4/go.mod h1:LMSpPZ6DbqWFxNCHW77HeMg9I646SAhApZ/wKdgO/C0=
@@ -2676,6 +2686,7 @@ google.golang.org/genproto v0.0.0-20200618031413-b414f8b61790/go.mod h1:jDfRM7Fc
 google.golang.org/genproto v0.0.0-20200726014623-da3ae01ef02d/go.mod h1:FWY/as6DDZQgahTzZj3fqbO1CbirC29ZNUFHwi0/+no=
 google.golang.org/genproto v0.0.0-20200729003335-053ba62fc06f/go.mod h1:FWY/as6DDZQgahTzZj3fqbO1CbirC29ZNUFHwi0/+no=
 google.golang.org/genproto v0.0.0-20200804131852-c06518451d9c/go.mod h1:FWY/as6DDZQgahTzZj3fqbO1CbirC29ZNUFHwi0/+no=
+google.golang.org/genproto v0.0.0-20200806141610-86f49bd18e98/go.mod h1:FWY/as6DDZQgahTzZj3fqbO1CbirC29ZNUFHwi0/+no=
 google.golang.org/genproto v0.0.0-20200825200019-8632dd797987/go.mod h1:FWY/as6DDZQgahTzZj3fqbO1CbirC29ZNUFHwi0/+no=
 google.golang.org/genproto v0.0.0-20200904004341-0bd0a958aa1d/go.mod h1:FWY/as6DDZQgahTzZj3fqbO1CbirC29ZNUFHwi0/+no=
 google.golang.org/genproto v0.0.0-20201019141844-1ed22bb0c154/go.mod h1:FWY/as6DDZQgahTzZj3fqbO1CbirC29ZNUFHwi0/+no=
@@ -2724,8 +2735,10 @@ google.golang.org/grpc v1.36.0/go.mod h1:qjiiYl8FncCW8feJPdyg3v6XW24KsRHe+dy9BAG
 google.golang.org/grpc v1.36.1/go.mod h1:qjiiYl8FncCW8feJPdyg3v6XW24KsRHe+dy9BAGRRjU=
 google.golang.org/grpc v1.38.0/go.mod h1:NREThFqKR1f3iQ6oBuvc5LadQuXVGo9rkm5ZGrQdJfM=
 google.golang.org/grpc v1.40.0/go.mod h1:ogyxbiOoUXAkP+4+xa6PZSE9DZgIHtSpzjDTB9KAK34=
-google.golang.org/grpc v1.41.0 h1:f+PlOh7QV4iIJkPrx5NQ7qaNGFQ3OTse67yaDHfju4E=
 google.golang.org/grpc v1.41.0/go.mod h1:U3l9uK9J0sini8mHphKoXyaqDA/8VyGnDee1zzIUK6k=
+google.golang.org/grpc v1.46.0 h1:oCjezcn6g6A75TGoKYBPgKmVBLexhYLM6MebdrPApP8=
+google.golang.org/grpc v1.46.0/go.mod h1:vN9eftEi1UMyUsIF80+uQXhHjbXYbm0uXoFCACuMGWk=
+google.golang.org/grpc/examples v0.0.0-20201130180447-c456688b1860/go.mod h1:Ly7ZA/ARzg8fnPU9TyZIxoz33sEUuWX7txiqs8lPTgE=
 google.golang.org/protobuf v0.0.0-20200109180630-ec00e32a8dfd/go.mod h1:DFci5gLYBciE7Vtevhsrf46CRTquxDuWsQurQQe4oz8=
 google.golang.org/protobuf v0.0.0-20200221191635-4d8936d0db64/go.mod h1:kwYJMbMJ01Woi6D6+Kah6886xMZcty6N08ah7+eCXa0=
 google.golang.org/protobuf v0.0.0-20200228230310-ab0ca4ff8a60/go.mod h1:cfTl7dwQJ+fmap5saPgwCLgHXTUD7jkjRqWcaiX5VyM=
@@ -2794,6 +2807,7 @@ gopkg.in/olivere/elastic.v5 v5.0.84/go.mod h1:LXF6q9XNBxpMqrcgax95C6xyARXWbbCXUr
 gopkg.in/resty.v1 v1.12.0/go.mod h1:mDo4pnntr5jdWRML875a/NmxYqAlA73dVijT2AXvQQo=
 gopkg.in/square/go-jose.v2 v2.2.2/go.mod h1:M9dMgbHiYLoDGQrXy7OpJDJWiKiU//h+vD76mk0e1AI=
 gopkg.in/square/go-jose.v2 v2.3.1/go.mod h1:M9dMgbHiYLoDGQrXy7OpJDJWiKiU//h+vD76mk0e1AI=
+gopkg.in/square/go-jose.v2 v2.4.1/go.mod h1:M9dMgbHiYLoDGQrXy7OpJDJWiKiU//h+vD76mk0e1AI=
 gopkg.in/square/go-jose.v2 v2.5.1/go.mod h1:M9dMgbHiYLoDGQrXy7OpJDJWiKiU//h+vD76mk0e1AI=
 gopkg.in/square/go-jose.v2 v2.6.0 h1:NGk74WTnPKBNUhNzQX7PYcTLUjoq7mzKk2OKbvwk2iI=
 gopkg.in/square/go-jose.v2 v2.6.0/go.mod h1:M9dMgbHiYLoDGQrXy7OpJDJWiKiU//h+vD76mk0e1AI=
diff --git a/integration/fixtures/k8s/01-traefik-crd.yml b/integration/fixtures/k8s/01-traefik-crd.yml
index 17dc336f6..983a678b8 100644
--- a/integration/fixtures/k8s/01-traefik-crd.yml
+++ b/integration/fixtures/k8s/01-traefik-crd.yml
@@ -1679,6 +1679,19 @@ spec:
                 description: ServerName defines the server name used to contact the
                   server.
                 type: string
+              spiffe:
+                description: Spiffe defines the SPIFFE configuration.
+                properties:
+                  ids:
+                    description: IDs defines the allowed SPIFFE IDs (takes precedence
+                      over the SPIFFE TrustDomain).
+                    items:
+                      type: string
+                    type: array
+                  trustDomain:
+                    description: TrustDomain defines the allowed SPIFFE trust domain.
+                    type: string
+                type: object
             type: object
         required:
         - metadata
diff --git a/integration/grpc_test.go b/integration/grpc_test.go
index 496f4b371..ab1c7f899 100644
--- a/integration/grpc_test.go
+++ b/integration/grpc_test.go
@@ -16,6 +16,7 @@ import (
 	"github.com/traefik/traefik/v2/pkg/log"
 	"google.golang.org/grpc"
 	"google.golang.org/grpc/credentials"
+	"google.golang.org/grpc/credentials/insecure"
 )
 
 var (
@@ -94,7 +95,7 @@ func getHelloClientGRPC() (helloworld.GreeterClient, func() error, error) {
 }
 
 func getHelloClientGRPCh2c() (helloworld.GreeterClient, func() error, error) {
-	conn, err := grpc.Dial("127.0.0.1:8081", grpc.WithInsecure())
+	conn, err := grpc.Dial("127.0.0.1:8081", grpc.WithTransportCredentials(insecure.NewCredentials()))
 	if err != nil {
 		return nil, func() error { return nil }, err
 	}
diff --git a/pkg/config/dynamic/http_config.go b/pkg/config/dynamic/http_config.go
index 376223e1c..f93c1a6a3 100644
--- a/pkg/config/dynamic/http_config.go
+++ b/pkg/config/dynamic/http_config.go
@@ -250,6 +250,17 @@ type ServersTransport struct {
 	ForwardingTimeouts  *ForwardingTimeouts        `description:"Timeouts for requests forwarded to the backend servers." json:"forwardingTimeouts,omitempty" toml:"forwardingTimeouts,omitempty" yaml:"forwardingTimeouts,omitempty" export:"true"`
 	DisableHTTP2        bool                       `description:"Disable HTTP/2 for connections with backend servers." json:"disableHTTP2,omitempty" toml:"disableHTTP2,omitempty" yaml:"disableHTTP2,omitempty" export:"true"`
 	PeerCertURI         string                     `description:"URI used to match against SAN URI during the peer certificate verification." json:"peerCertURI,omitempty" toml:"peerCertURI,omitempty" yaml:"peerCertURI,omitempty" export:"true"`
+	Spiffe              *Spiffe                    `description:"Define the SPIFFE configuration." json:"spiffe,omitempty" toml:"spiffe,omitempty" yaml:"spiffe,omitempty" label:"allowEmpty" file:"allowEmpty" export:"true"`
+}
+
+// +k8s:deepcopy-gen=true
+
+// Spiffe holds the SPIFFE configuration.
+type Spiffe struct {
+	// IDs defines the allowed SPIFFE IDs (takes precedence over the SPIFFE TrustDomain).
+	IDs []string `description:"Defines the allowed SPIFFE IDs (takes precedence over the SPIFFE TrustDomain)." json:"ids,omitempty" toml:"ids,omitempty" yaml:"ids,omitempty"`
+	// TrustDomain defines the allowed SPIFFE trust domain.
+	TrustDomain string `description:"Defines the allowed SPIFFE trust domain." json:"trustDomain,omitempty" yaml:"trustDomain,omitempty" toml:"trustDomain,omitempty"`
 }
 
 // +k8s:deepcopy-gen=true
diff --git a/pkg/config/dynamic/zz_generated.deepcopy.go b/pkg/config/dynamic/zz_generated.deepcopy.go
index 587048180..adba5a4ee 100644
--- a/pkg/config/dynamic/zz_generated.deepcopy.go
+++ b/pkg/config/dynamic/zz_generated.deepcopy.go
@@ -1161,6 +1161,11 @@ func (in *ServersTransport) DeepCopyInto(out *ServersTransport) {
 		*out = new(ForwardingTimeouts)
 		**out = **in
 	}
+	if in.Spiffe != nil {
+		in, out := &in.Spiffe, &out.Spiffe
+		*out = new(Spiffe)
+		(*in).DeepCopyInto(*out)
+	}
 	return
 }
 
@@ -1231,6 +1236,27 @@ func (in *SourceCriterion) DeepCopy() *SourceCriterion {
 	return out
 }
 
+// DeepCopyInto is an autogenerated deepcopy function, copying the receiver, writing into out. in must be non-nil.
+func (in *Spiffe) DeepCopyInto(out *Spiffe) {
+	*out = *in
+	if in.IDs != nil {
+		in, out := &in.IDs, &out.IDs
+		*out = make([]string, len(*in))
+		copy(*out, *in)
+	}
+	return
+}
+
+// DeepCopy is an autogenerated deepcopy function, copying the receiver, creating a new Spiffe.
+func (in *Spiffe) DeepCopy() *Spiffe {
+	if in == nil {
+		return nil
+	}
+	out := new(Spiffe)
+	in.DeepCopyInto(out)
+	return out
+}
+
 // DeepCopyInto is an autogenerated deepcopy function, copying the receiver, writing into out. in must be non-nil.
 func (in *Sticky) DeepCopyInto(out *Sticky) {
 	*out = *in
diff --git a/pkg/config/static/static_config.go b/pkg/config/static/static_config.go
index 4d803b2ad..4a2558b8b 100644
--- a/pkg/config/static/static_config.go
+++ b/pkg/config/static/static_config.go
@@ -84,6 +84,13 @@ type Configuration struct {
 	Hub *hub.Provider `description:"Traefik Hub configuration." json:"hub,omitempty" toml:"hub,omitempty" yaml:"hub,omitempty" label:"allowEmpty" file:"allowEmpty" export:"true"`
 
 	Experimental *Experimental `description:"experimental features." json:"experimental,omitempty" toml:"experimental,omitempty" yaml:"experimental,omitempty" export:"true"`
+
+	Spiffe *SpiffeClientConfig `description:"SPIFFE integration configuration." json:"spiffe,omitempty" toml:"spiffe,omitempty" yaml:"spiffe,omitempty" export:"true"`
+}
+
+// SpiffeClientConfig defines the SPIFFE client configuration.
+type SpiffeClientConfig struct {
+	WorkloadAPIAddr string `description:"Defines the workload API address." json:"workloadAPIAddr,omitempty" toml:"workloadAPIAddr,omitempty" yaml:"workloadAPIAddr,omitempty"`
 }
 
 // CertificateResolver contains the configuration for the different types of certificates resolver.
@@ -104,6 +111,13 @@ type ServersTransport struct {
 	RootCAs             []tls.FileOrContent `description:"Add cert file for self-signed certificate." json:"rootCAs,omitempty" toml:"rootCAs,omitempty" yaml:"rootCAs,omitempty"`
 	MaxIdleConnsPerHost int                 `description:"If non-zero, controls the maximum idle (keep-alive) to keep per-host. If zero, DefaultMaxIdleConnsPerHost is used" json:"maxIdleConnsPerHost,omitempty" toml:"maxIdleConnsPerHost,omitempty" yaml:"maxIdleConnsPerHost,omitempty" export:"true"`
 	ForwardingTimeouts  *ForwardingTimeouts `description:"Timeouts for requests forwarded to the backend servers." json:"forwardingTimeouts,omitempty" toml:"forwardingTimeouts,omitempty" yaml:"forwardingTimeouts,omitempty" export:"true"`
+	Spiffe              *Spiffe             `description:"Defines the SPIFFE configuration." json:"spiffe,omitempty" toml:"spiffe,omitempty" yaml:"spiffe,omitempty" label:"allowEmpty" file:"allowEmpty" export:"true"`
+}
+
+// Spiffe holds the SPIFFE configuration.
+type Spiffe struct {
+	IDs         []string `description:"Defines the allowed SPIFFE IDs (takes precedence over the SPIFFE TrustDomain)." json:"ids,omitempty" toml:"ids,omitempty" yaml:"ids,omitempty"`
+	TrustDomain string   `description:"Defines the allowed SPIFFE trust domain." json:"trustDomain,omitempty" yaml:"trustDomain,omitempty" toml:"trustDomain,omitempty"`
 }
 
 // API holds the API configuration.
diff --git a/pkg/healthcheck/healthcheck.go b/pkg/healthcheck/healthcheck.go
index 36178ce98..d3dc851bd 100644
--- a/pkg/healthcheck/healthcheck.go
+++ b/pkg/healthcheck/healthcheck.go
@@ -21,6 +21,7 @@ import (
 	"github.com/vulcand/oxy/roundrobin"
 	"google.golang.org/grpc"
 	"google.golang.org/grpc/codes"
+	"google.golang.org/grpc/credentials/insecure"
 	healthpb "google.golang.org/grpc/health/grpc_health_v1"
 	"google.golang.org/grpc/status"
 )
@@ -317,7 +318,7 @@ func checkHealthGRPC(serverURL *url.URL, backend *BackendConfig) error {
 	var opts []grpc.DialOption
 	switch backend.Options.Scheme {
 	case "http", "h2c", "":
-		opts = append(opts, grpc.WithInsecure())
+		opts = append(opts, grpc.WithTransportCredentials(insecure.NewCredentials()))
 	}
 
 	ctx, cancel := context.WithTimeout(context.Background(), backend.Options.Timeout)
diff --git a/pkg/provider/kubernetes/crd/fixtures/with_servers_transport.yml b/pkg/provider/kubernetes/crd/fixtures/with_servers_transport.yml
index 04d9b4e05..fdbf7b930 100644
--- a/pkg/provider/kubernetes/crd/fixtures/with_servers_transport.yml
+++ b/pkg/provider/kubernetes/crd/fixtures/with_servers_transport.yml
@@ -112,6 +112,11 @@ spec:
     idleConnTimeout: 42ms
     readIdleTimeout: 42s
     pingTimeout: 42s
+  spiffe:
+    ids:
+      - spiffe://foo/buz
+      - spiffe://bar/biz
+    trustDomain: spiffe://lol
 
 ---
 apiVersion: traefik.containo.us/v1alpha1
@@ -144,4 +149,3 @@ spec:
         - name: whoamitls
           port: 443
           serversTransport: default-test
-
diff --git a/pkg/provider/kubernetes/crd/kubernetes.go b/pkg/provider/kubernetes/crd/kubernetes.go
index a43345e67..ff6c6b588 100644
--- a/pkg/provider/kubernetes/crd/kubernetes.go
+++ b/pkg/provider/kubernetes/crd/kubernetes.go
@@ -381,6 +381,7 @@ func (p *Provider) loadConfigurationFromCRD(ctx context.Context, client Client)
 			MaxIdleConnsPerHost: serversTransport.Spec.MaxIdleConnsPerHost,
 			ForwardingTimeouts:  forwardingTimeout,
 			PeerCertURI:         serversTransport.Spec.PeerCertURI,
+			Spiffe:              serversTransport.Spec.Spiffe,
 		}
 	}
 
diff --git a/pkg/provider/kubernetes/crd/kubernetes_test.go b/pkg/provider/kubernetes/crd/kubernetes_test.go
index 7465c8fae..60c079406 100644
--- a/pkg/provider/kubernetes/crd/kubernetes_test.go
+++ b/pkg/provider/kubernetes/crd/kubernetes_test.go
@@ -3916,6 +3916,13 @@ func TestLoadIngressRoutes(t *testing.T) {
 								PingTimeout:           ptypes.Duration(42 * time.Second),
 							},
 							PeerCertURI: "foo://bar",
+							Spiffe: &dynamic.Spiffe{
+								IDs: []string{
+									"spiffe://foo/buz",
+									"spiffe://bar/biz",
+								},
+								TrustDomain: "spiffe://lol",
+							},
 						},
 						"default-test": {
 							ServerName: "test",
diff --git a/pkg/provider/kubernetes/crd/traefik/v1alpha1/serverstransport.go b/pkg/provider/kubernetes/crd/traefik/v1alpha1/serverstransport.go
index 20bc7d18a..10486a426 100644
--- a/pkg/provider/kubernetes/crd/traefik/v1alpha1/serverstransport.go
+++ b/pkg/provider/kubernetes/crd/traefik/v1alpha1/serverstransport.go
@@ -1,6 +1,7 @@
 package v1alpha1
 
 import (
+	"github.com/traefik/traefik/v2/pkg/config/dynamic"
 	metav1 "k8s.io/apimachinery/pkg/apis/meta/v1"
 	"k8s.io/apimachinery/pkg/util/intstr"
 )
@@ -42,6 +43,8 @@ type ServersTransportSpec struct {
 	DisableHTTP2 bool `json:"disableHTTP2,omitempty"`
 	// PeerCertURI defines the peer cert URI used to match against SAN URI during the peer certificate verification.
 	PeerCertURI string `json:"peerCertURI,omitempty"`
+	// Spiffe defines the SPIFFE configuration.
+	Spiffe *dynamic.Spiffe `json:"spiffe,omitempty"`
 }
 
 // +k8s:deepcopy-gen=true
diff --git a/pkg/provider/kubernetes/crd/traefik/v1alpha1/zz_generated.deepcopy.go b/pkg/provider/kubernetes/crd/traefik/v1alpha1/zz_generated.deepcopy.go
index 5cc7903fc..5dbd71621 100644
--- a/pkg/provider/kubernetes/crd/traefik/v1alpha1/zz_generated.deepcopy.go
+++ b/pkg/provider/kubernetes/crd/traefik/v1alpha1/zz_generated.deepcopy.go
@@ -1142,6 +1142,11 @@ func (in *ServersTransportSpec) DeepCopyInto(out *ServersTransportSpec) {
 		*out = new(ForwardingTimeouts)
 		(*in).DeepCopyInto(*out)
 	}
+	if in.Spiffe != nil {
+		in, out := &in.Spiffe, &out.Spiffe
+		*out = new(dynamic.Spiffe)
+		(*in).DeepCopyInto(*out)
+	}
 	return
 }
 
diff --git a/pkg/provider/traefik/internal.go b/pkg/provider/traefik/internal.go
index 47d2c3023..0c8d5aca0 100644
--- a/pkg/provider/traefik/internal.go
+++ b/pkg/provider/traefik/internal.go
@@ -322,6 +322,13 @@ func (i *Provider) serverTransport(cfg *dynamic.Configuration) {
 		MaxIdleConnsPerHost: i.staticCfg.ServersTransport.MaxIdleConnsPerHost,
 	}
 
+	if i.staticCfg.Spiffe != nil {
+		st.Spiffe = &dynamic.Spiffe{
+			IDs:         i.staticCfg.ServersTransport.Spiffe.IDs,
+			TrustDomain: i.staticCfg.ServersTransport.Spiffe.TrustDomain,
+		}
+	}
+
 	if i.staticCfg.ServersTransport.ForwardingTimeouts != nil {
 		st.ForwardingTimeouts = &dynamic.ForwardingTimeouts{
 			DialTimeout:           i.staticCfg.ServersTransport.ForwardingTimeouts.DialTimeout,
diff --git a/pkg/server/router/router_test.go b/pkg/server/router/router_test.go
index 867da0a9b..383fac0c2 100644
--- a/pkg/server/router/router_test.go
+++ b/pkg/server/router/router_test.go
@@ -312,7 +312,7 @@ func TestRouterManager_Get(t *testing.T) {
 				},
 			})
 
-			roundTripperManager := service.NewRoundTripperManager()
+			roundTripperManager := service.NewRoundTripperManager(nil)
 			roundTripperManager.Update(map[string]*dynamic.ServersTransport{"default@internal": {}})
 			serviceManager := service.NewManager(rtConf.Services, nil, nil, roundTripperManager)
 			middlewaresBuilder := middleware.NewBuilder(rtConf.Middlewares, serviceManager, nil)
@@ -418,7 +418,7 @@ func TestAccessLog(t *testing.T) {
 				},
 			})
 
-			roundTripperManager := service.NewRoundTripperManager()
+			roundTripperManager := service.NewRoundTripperManager(nil)
 			roundTripperManager.Update(map[string]*dynamic.ServersTransport{"default@internal": {}})
 			serviceManager := service.NewManager(rtConf.Services, nil, nil, roundTripperManager)
 			middlewaresBuilder := middleware.NewBuilder(rtConf.Middlewares, serviceManager, nil)
@@ -713,7 +713,7 @@ func TestRuntimeConfiguration(t *testing.T) {
 				},
 			})
 
-			roundTripperManager := service.NewRoundTripperManager()
+			roundTripperManager := service.NewRoundTripperManager(nil)
 			roundTripperManager.Update(map[string]*dynamic.ServersTransport{"default@internal": {}})
 			serviceManager := service.NewManager(rtConf.Services, nil, nil, roundTripperManager)
 			middlewaresBuilder := middleware.NewBuilder(rtConf.Middlewares, serviceManager, nil)
@@ -788,7 +788,7 @@ func TestProviderOnMiddlewares(t *testing.T) {
 		},
 	})
 
-	roundTripperManager := service.NewRoundTripperManager()
+	roundTripperManager := service.NewRoundTripperManager(nil)
 	roundTripperManager.Update(map[string]*dynamic.ServersTransport{"default@internal": {}})
 	serviceManager := service.NewManager(rtConf.Services, nil, nil, roundTripperManager)
 	middlewaresBuilder := middleware.NewBuilder(rtConf.Middlewares, serviceManager, nil)
diff --git a/pkg/server/routerfactory_test.go b/pkg/server/routerfactory_test.go
index 0c6697e38..0afa69584 100644
--- a/pkg/server/routerfactory_test.go
+++ b/pkg/server/routerfactory_test.go
@@ -48,7 +48,7 @@ func TestReuseService(t *testing.T) {
 		),
 	)
 
-	roundTripperManager := service.NewRoundTripperManager()
+	roundTripperManager := service.NewRoundTripperManager(nil)
 	roundTripperManager.Update(map[string]*dynamic.ServersTransport{"default@internal": {}})
 	managerFactory := service.NewManagerFactory(staticConfig, nil, metrics.NewVoidRegistry(), roundTripperManager, nil)
 	tlsManager := tls.NewManager()
@@ -184,7 +184,7 @@ func TestServerResponseEmptyBackend(t *testing.T) {
 				},
 			}
 
-			roundTripperManager := service.NewRoundTripperManager()
+			roundTripperManager := service.NewRoundTripperManager(nil)
 			roundTripperManager.Update(map[string]*dynamic.ServersTransport{"default@internal": {}})
 			managerFactory := service.NewManagerFactory(staticConfig, nil, metrics.NewVoidRegistry(), roundTripperManager, nil)
 			tlsManager := tls.NewManager()
@@ -225,7 +225,7 @@ func TestInternalServices(t *testing.T) {
 		),
 	)
 
-	roundTripperManager := service.NewRoundTripperManager()
+	roundTripperManager := service.NewRoundTripperManager(nil)
 	roundTripperManager.Update(map[string]*dynamic.ServersTransport{"default@internal": {}})
 	managerFactory := service.NewManagerFactory(staticConfig, nil, metrics.NewVoidRegistry(), roundTripperManager, nil)
 	tlsManager := tls.NewManager()
diff --git a/pkg/server/service/roundtripper.go b/pkg/server/service/roundtripper.go
index 68b3b0bbf..b155a5632 100644
--- a/pkg/server/service/roundtripper.go
+++ b/pkg/server/service/roundtripper.go
@@ -11,6 +11,10 @@ import (
 	"sync"
 	"time"
 
+	"github.com/spiffe/go-spiffe/v2/bundle/x509bundle"
+	"github.com/spiffe/go-spiffe/v2/spiffeid"
+	"github.com/spiffe/go-spiffe/v2/spiffetls/tlsconfig"
+	"github.com/spiffe/go-spiffe/v2/svid/x509svid"
 	"github.com/traefik/traefik/v2/pkg/config/dynamic"
 	"github.com/traefik/traefik/v2/pkg/log"
 	traefiktls "github.com/traefik/traefik/v2/pkg/tls"
@@ -26,11 +30,18 @@ func (t *h2cTransportWrapper) RoundTrip(req *http.Request) (*http.Response, erro
 	return t.Transport.RoundTrip(req)
 }
 
+// SpiffeX509Source allows to retrieve a x509 SVID and bundle.
+type SpiffeX509Source interface {
+	x509svid.Source
+	x509bundle.Source
+}
+
 // NewRoundTripperManager creates a new RoundTripperManager.
-func NewRoundTripperManager() *RoundTripperManager {
+func NewRoundTripperManager(spiffeX509Source SpiffeX509Source) *RoundTripperManager {
 	return &RoundTripperManager{
-		roundTrippers: make(map[string]http.RoundTripper),
-		configs:       make(map[string]*dynamic.ServersTransport),
+		roundTrippers:    make(map[string]http.RoundTripper),
+		configs:          make(map[string]*dynamic.ServersTransport),
+		spiffeX509Source: spiffeX509Source,
 	}
 }
 
@@ -39,6 +50,8 @@ type RoundTripperManager struct {
 	rtLock        sync.RWMutex
 	roundTrippers map[string]http.RoundTripper
 	configs       map[string]*dynamic.ServersTransport
+
+	spiffeX509Source SpiffeX509Source
 }
 
 // Update updates the roundtrippers configurations.
@@ -59,7 +72,7 @@ func (r *RoundTripperManager) Update(newConfigs map[string]*dynamic.ServersTrans
 		}
 
 		var err error
-		r.roundTrippers[configName], err = createRoundTripper(newConfig)
+		r.roundTrippers[configName], err = r.createRoundTripper(newConfig)
 		if err != nil {
 			log.WithoutContext().Errorf("Could not configure HTTP Transport %s, fallback on default transport: %v", configName, err)
 			r.roundTrippers[configName] = http.DefaultTransport
@@ -72,7 +85,7 @@ func (r *RoundTripperManager) Update(newConfigs map[string]*dynamic.ServersTrans
 		}
 
 		var err error
-		r.roundTrippers[newConfigName], err = createRoundTripper(newConfig)
+		r.roundTrippers[newConfigName], err = r.createRoundTripper(newConfig)
 		if err != nil {
 			log.WithoutContext().Errorf("Could not configure HTTP Transport %s, fallback on default transport: %v", newConfigName, err)
 			r.roundTrippers[newConfigName] = http.DefaultTransport
@@ -102,7 +115,7 @@ func (r *RoundTripperManager) Get(name string) (http.RoundTripper, error) {
 // For the settings that can't be configured in Traefik it uses the default http.Transport settings.
 // An exception to this is the MaxIdleConns setting as we only provide the option MaxIdleConnsPerHost in Traefik at this point in time.
 // Setting this value to the default of 100 could lead to confusing behavior and backwards compatibility issues.
-func createRoundTripper(cfg *dynamic.ServersTransport) (http.RoundTripper, error) {
+func (r *RoundTripperManager) createRoundTripper(cfg *dynamic.ServersTransport) (http.RoundTripper, error) {
 	if cfg == nil {
 		return nil, errors.New("no transport configuration given")
 	}
@@ -132,7 +145,24 @@ func createRoundTripper(cfg *dynamic.ServersTransport) (http.RoundTripper, error
 		transport.IdleConnTimeout = time.Duration(cfg.ForwardingTimeouts.IdleConnTimeout)
 	}
 
+	if cfg.Spiffe != nil {
+		if r.spiffeX509Source == nil {
+			return nil, errors.New("SPIFFE is enabled for this transport, but not configured")
+		}
+
+		spiffeAuthorizer, err := buildSpiffeAuthorizer(cfg.Spiffe)
+		if err != nil {
+			return nil, fmt.Errorf("unable to build SPIFFE authorizer: %w", err)
+		}
+
+		transport.TLSClientConfig = tlsconfig.MTLSClientConfig(r.spiffeX509Source, r.spiffeX509Source, spiffeAuthorizer)
+	}
+
 	if cfg.InsecureSkipVerify || len(cfg.RootCAs) > 0 || len(cfg.ServerName) > 0 || len(cfg.Certificates) > 0 || cfg.PeerCertURI != "" {
+		if transport.TLSClientConfig != nil {
+			return nil, errors.New("TLS and SPIFFE configuration cannot be defined at the same time")
+		}
+
 		transport.TLSClientConfig = &tls.Config{
 			ServerName:         cfg.ServerName,
 			InsecureSkipVerify: cfg.InsecureSkipVerify,
@@ -173,3 +203,31 @@ func createRootCACertPool(rootCAs []traefiktls.FileOrContent) *x509.CertPool {
 
 	return roots
 }
+
+func buildSpiffeAuthorizer(cfg *dynamic.Spiffe) (tlsconfig.Authorizer, error) {
+	switch {
+	case len(cfg.IDs) > 0:
+		spiffeIDs := make([]spiffeid.ID, 0, len(cfg.IDs))
+		for _, rawID := range cfg.IDs {
+			id, err := spiffeid.FromString(rawID)
+			if err != nil {
+				return nil, fmt.Errorf("invalid SPIFFE ID: %w", err)
+			}
+
+			spiffeIDs = append(spiffeIDs, id)
+		}
+
+		return tlsconfig.AuthorizeOneOf(spiffeIDs...), nil
+
+	case cfg.TrustDomain != "":
+		trustDomain, err := spiffeid.TrustDomainFromString(cfg.TrustDomain)
+		if err != nil {
+			return nil, fmt.Errorf("invalid SPIFFE trust domain: %w", err)
+		}
+
+		return tlsconfig.AuthorizeMemberOf(trustDomain), nil
+
+	default:
+		return tlsconfig.AuthorizeAny(), nil
+	}
+}
diff --git a/pkg/server/service/roundtripper_test.go b/pkg/server/service/roundtripper_test.go
index a057166ab..37d543674 100644
--- a/pkg/server/service/roundtripper_test.go
+++ b/pkg/server/service/roundtripper_test.go
@@ -1,14 +1,24 @@
 package service
 
 import (
+	"crypto/rand"
+	"crypto/rsa"
 	"crypto/tls"
 	"crypto/x509"
+	"crypto/x509/pkix"
+	"math/big"
 	"net"
 	"net/http"
 	"net/http/httptest"
+	"net/url"
 	"sync/atomic"
 	"testing"
+	"time"
 
+	"github.com/spiffe/go-spiffe/v2/bundle/x509bundle"
+	"github.com/spiffe/go-spiffe/v2/spiffeid"
+	"github.com/spiffe/go-spiffe/v2/spiffetls/tlsconfig"
+	"github.com/spiffe/go-spiffe/v2/svid/x509svid"
 	"github.com/stretchr/testify/assert"
 	"github.com/stretchr/testify/require"
 	"github.com/traefik/traefik/v2/pkg/config/dynamic"
@@ -129,7 +139,7 @@ func TestKeepConnectionWhenSameConfiguration(t *testing.T) {
 	srv.TLS = &tls.Config{Certificates: []tls.Certificate{cert}}
 	srv.StartTLS()
 
-	rtManager := NewRoundTripperManager()
+	rtManager := NewRoundTripperManager(nil)
 
 	dynamicConf := map[string]*dynamic.ServersTransport{
 		"test": {
@@ -197,7 +207,7 @@ func TestMTLS(t *testing.T) {
 	}
 	srv.StartTLS()
 
-	rtManager := NewRoundTripperManager()
+	rtManager := NewRoundTripperManager(nil)
 
 	dynamicConf := map[string]*dynamic.ServersTransport{
 		"test": {
@@ -228,6 +238,141 @@ func TestMTLS(t *testing.T) {
 	assert.Equal(t, http.StatusOK, resp.StatusCode)
 }
 
+func TestSpiffeMTLS(t *testing.T) {
+	srv := httptest.NewUnstartedServer(http.HandlerFunc(func(rw http.ResponseWriter, req *http.Request) {
+		rw.WriteHeader(http.StatusOK)
+	}))
+
+	trustDomain := spiffeid.RequireTrustDomainFromString("spiffe://traefik.test")
+
+	pki, err := newFakeSpiffePKI(trustDomain)
+	require.NoError(t, err)
+
+	clientSVID, err := pki.genSVID(spiffeid.RequireFromPath(trustDomain, "/client"))
+	require.NoError(t, err)
+
+	serverSVID, err := pki.genSVID(spiffeid.RequireFromPath(trustDomain, "/server"))
+	require.NoError(t, err)
+
+	serverSource := fakeSpiffeSource{
+		svid:   serverSVID,
+		bundle: pki.bundle,
+	}
+
+	// go-spiffe's `tlsconfig.MTLSServerConfig` (that should be used here) does not set a certificate on
+	// the returned `tls.Config` and relies instead on `GetCertificate` being always called.
+	// But it turns out that `StartTLS` from `httptest.Server`, enforces a default certificate
+	// if no certificate is previously set on the configured TLS config.
+	// It makes the test server always serve the httptest default certificate, and not the SPIFFE certificate,
+	// as GetCertificate is in that case never called (there's a default cert, and SNI is not used).
+	// To bypass this issue, we're manually extracting the server ceritificate from the server SVID
+	// and use another initialization method that forces serving the server SPIFFE certificate.
+	serverCert, err := tlsconfig.GetCertificate(&serverSource)(nil)
+	require.NoError(t, err)
+	srv.TLS = tlsconfig.MTLSWebServerConfig(
+		serverCert,
+		&serverSource,
+		tlsconfig.AuthorizeAny(),
+	)
+	srv.StartTLS()
+	defer srv.Close()
+
+	clientSource := fakeSpiffeSource{
+		svid:   clientSVID,
+		bundle: pki.bundle,
+	}
+
+	testCases := []struct {
+		desc             string
+		config           dynamic.Spiffe
+		clientSource     SpiffeX509Source
+		wantStatusCode   int
+		wantErrorMessage string
+	}{
+		{
+			desc:           "supports SPIFFE mTLS",
+			config:         dynamic.Spiffe{},
+			clientSource:   &clientSource,
+			wantStatusCode: http.StatusOK,
+		},
+		{
+			desc: "allows expected server SPIFFE ID",
+			config: dynamic.Spiffe{
+				IDs: []string{"spiffe://traefik.test/server"},
+			},
+			clientSource:   &clientSource,
+			wantStatusCode: http.StatusOK,
+		},
+		{
+			desc: "blocks unexpected server SPIFFE ID",
+			config: dynamic.Spiffe{
+				IDs: []string{"spiffe://traefik.test/not-server"},
+			},
+			clientSource:     &clientSource,
+			wantErrorMessage: `unexpected ID "spiffe://traefik.test/server"`,
+		},
+		{
+			desc: "allows expected server trust domain",
+			config: dynamic.Spiffe{
+				TrustDomain: "spiffe://traefik.test",
+			},
+			clientSource:   &clientSource,
+			wantStatusCode: http.StatusOK,
+		},
+		{
+			desc: "denies unexpected server trust domain",
+			config: dynamic.Spiffe{
+				TrustDomain: "spiffe://not-traefik.test",
+			},
+			clientSource:     &clientSource,
+			wantErrorMessage: `unexpected trust domain "traefik.test"`,
+		},
+		{
+			desc: "spiffe IDs allowlist takes precedence",
+			config: dynamic.Spiffe{
+				IDs:         []string{"spiffe://traefik.test/not-server"},
+				TrustDomain: "spiffe://not-traefik.test",
+			},
+			clientSource:     &clientSource,
+			wantErrorMessage: `unexpected ID "spiffe://traefik.test/server"`,
+		},
+		{
+			desc:             "raises an error when spiffe is enabled on the transport but no workloadapi address is given",
+			config:           dynamic.Spiffe{},
+			clientSource:     nil,
+			wantErrorMessage: `remote error: tls: bad certificate`,
+		},
+	}
+
+	for _, test := range testCases {
+		t.Run(test.desc, func(t *testing.T) {
+			rtManager := NewRoundTripperManager(test.clientSource)
+
+			dynamicConf := map[string]*dynamic.ServersTransport{
+				"test": {
+					Spiffe: &test.config,
+				},
+			}
+
+			rtManager.Update(dynamicConf)
+
+			tr, err := rtManager.Get("test")
+			require.NoError(t, err)
+
+			client := http.Client{Transport: tr}
+
+			resp, err := client.Get(srv.URL)
+			if test.wantErrorMessage != "" {
+				assert.ErrorContains(t, err, test.wantErrorMessage)
+				return
+			}
+
+			require.NoError(t, err)
+			assert.Equal(t, test.wantStatusCode, resp.StatusCode)
+		})
+	}
+}
+
 func TestDisableHTTP2(t *testing.T) {
 	testCases := []struct {
 		desc          string
@@ -269,7 +414,7 @@ func TestDisableHTTP2(t *testing.T) {
 			srv.EnableHTTP2 = test.serverHTTP2
 			srv.StartTLS()
 
-			rtManager := NewRoundTripperManager()
+			rtManager := NewRoundTripperManager(nil)
 
 			dynamicConf := map[string]*dynamic.ServersTransport{
 				"test": {
@@ -293,3 +438,116 @@ func TestDisableHTTP2(t *testing.T) {
 		})
 	}
 }
+
+// fakeSpiffePKI simulates a SPIFFE aware PKI and allows generating multiple valid SVIDs.
+type fakeSpiffePKI struct {
+	caPrivateKey *rsa.PrivateKey
+
+	bundle *x509bundle.Bundle
+}
+
+func newFakeSpiffePKI(trustDomain spiffeid.TrustDomain) (fakeSpiffePKI, error) {
+	caPrivateKey, err := rsa.GenerateKey(rand.Reader, 2048)
+	if err != nil {
+		return fakeSpiffePKI{}, err
+	}
+
+	caTemplate := x509.Certificate{
+		SerialNumber: big.NewInt(2000),
+		Subject: pkix.Name{
+			Organization: []string{"spiffe"},
+		},
+		URIs:         []*url.URL{spiffeid.RequireFromPath(trustDomain, "/ca").URL()},
+		NotBefore:    time.Now(),
+		NotAfter:     time.Now().Add(time.Hour),
+		SubjectKeyId: []byte("ca"),
+		KeyUsage: x509.KeyUsageCertSign |
+			x509.KeyUsageCRLSign,
+		BasicConstraintsValid: true,
+		IsCA:                  true,
+		PublicKey:             caPrivateKey.Public(),
+	}
+	if err != nil {
+		return fakeSpiffePKI{}, err
+	}
+
+	caCertDER, err := x509.CreateCertificate(
+		rand.Reader,
+		&caTemplate,
+		&caTemplate,
+		caPrivateKey.Public(),
+		caPrivateKey,
+	)
+	if err != nil {
+		return fakeSpiffePKI{}, err
+	}
+
+	bundle, err := x509bundle.ParseRaw(
+		trustDomain,
+		caCertDER,
+	)
+	if err != nil {
+		return fakeSpiffePKI{}, err
+	}
+
+	return fakeSpiffePKI{
+		bundle:       bundle,
+		caPrivateKey: caPrivateKey,
+	}, nil
+}
+
+func (f *fakeSpiffePKI) genSVID(id spiffeid.ID) (*x509svid.SVID, error) {
+	privateKey, err := rsa.GenerateKey(rand.Reader, 2048)
+	if err != nil {
+		return nil, err
+	}
+
+	template := x509.Certificate{
+		SerialNumber: big.NewInt(200001),
+		URIs:         []*url.URL{id.URL()},
+		NotBefore:    time.Now(),
+		NotAfter:     time.Now().Add(time.Hour),
+		SubjectKeyId: []byte("svid"),
+		KeyUsage: x509.KeyUsageKeyEncipherment |
+			x509.KeyUsageKeyAgreement |
+			x509.KeyUsageDigitalSignature,
+		ExtKeyUsage: []x509.ExtKeyUsage{
+			x509.ExtKeyUsageServerAuth,
+			x509.ExtKeyUsageClientAuth,
+		},
+		BasicConstraintsValid: true,
+		PublicKey:             privateKey.PublicKey,
+	}
+
+	certDER, err := x509.CreateCertificate(
+		rand.Reader,
+		&template,
+		f.bundle.X509Authorities()[0],
+		privateKey.Public(),
+		f.caPrivateKey,
+	)
+	if err != nil {
+		return nil, err
+	}
+
+	keyPKCS8, err := x509.MarshalPKCS8PrivateKey(privateKey)
+	if err != nil {
+		return nil, err
+	}
+
+	return x509svid.ParseRaw(certDER, keyPKCS8)
+}
+
+// fakeSpiffeSource allows retrieving staticly an SVID and its associated bundle.
+type fakeSpiffeSource struct {
+	bundle *x509bundle.Bundle
+	svid   *x509svid.SVID
+}
+
+func (s *fakeSpiffeSource) GetX509BundleForTrustDomain(trustDomain spiffeid.TrustDomain) (*x509bundle.Bundle, error) {
+	return s.bundle, nil
+}
+
+func (s *fakeSpiffeSource) GetX509SVID() (*x509svid.SVID, error) {
+	return s.svid, nil
+}