diff --git a/pkg/middlewares/replacepathregex/replace_path_regex.go b/pkg/middlewares/replacepathregex/replace_path_regex.go
index fea6fa2de..fb2c47189 100644
--- a/pkg/middlewares/replacepathregex/replace_path_regex.go
+++ b/pkg/middlewares/replacepathregex/replace_path_regex.go
@@ -53,7 +53,7 @@ func (rp *replacePathRegex) ServeHTTP(rw http.ResponseWriter, req *http.Request)
 		currentPath = req.URL.EscapedPath()
 	}
 
-	if rp.regexp != nil && len(rp.replacement) > 0 && rp.regexp.MatchString(currentPath) {
+	if rp.regexp != nil && rp.regexp.MatchString(currentPath) {
 		req.Header.Add(replacepath.ReplacedPathHeader, currentPath)
 		req.URL.RawPath = rp.regexp.ReplaceAllString(currentPath, rp.replacement)
 
diff --git a/pkg/middlewares/replacepathregex/replace_path_regex_test.go b/pkg/middlewares/replacepathregex/replace_path_regex_test.go
index 59018d784..b7e637851 100644
--- a/pkg/middlewares/replacepathregex/replace_path_regex_test.go
+++ b/pkg/middlewares/replacepathregex/replace_path_regex_test.go
@@ -44,6 +44,28 @@ func TestReplacePathRegex(t *testing.T) {
 			expectedRawPath: "/who-am-i/and/who-am-i",
 			expectedHeader:  "/whoami/and/whoami",
 		},
+		{
+			desc: "empty replacement",
+			path: "/whoami/and/whoami",
+			config: dynamic.ReplacePathRegex{
+				Replacement: "",
+				Regex:       `/whoami`,
+			},
+			expectedPath:    "/and",
+			expectedRawPath: "/and",
+			expectedHeader:  "/whoami/and/whoami",
+		},
+		{
+			desc: "empty trimmed replacement",
+			path: "/whoami/and/whoami",
+			config: dynamic.ReplacePathRegex{
+				Replacement: " ",
+				Regex:       `/whoami`,
+			},
+			expectedPath:    "/and",
+			expectedRawPath: "/and",
+			expectedHeader:  "/whoami/and/whoami",
+		},
 		{
 			desc: "no match",
 			path: "/whoami/and/whoami",